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Bioceramic cement in the filling of bone defects in rats1

Christiano Cândido ZerbinattiI , Daniela Francescato VeigaII , Monique Amanda Bastista OliveiraIII , Fiorita Gonzales Lopes MundimIV , Rodrigo Machado PereiraV , Francisco AzevedoVI , Taylor Brandão SchnaiderVII , José Dias da Silva NetoVIII


 

I DDS, Master, Professional Masters in Sciences Applied to Health, Universidade Vale do Sapucaí (UNIVÁS), Pouso Alegre-MG, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; manuscript preparation.

II PhD, Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Critical revision, final approval.

III Graduate student, Biological Sciences, UNIVÁS, Pouso Alegre-MG, Brazil. Technical procedures.

IV PhD, Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Histopathological examinations.

V Master, Biological Sciences, UNIVÁS, Pouso Alegre-MG, Brazil.Ttechnical procedures, histological examinations, manuscript writing.

VI DDS, Master, Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Technical procedures, statistics analysis.

VII PhD, Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Technical procedures, statistics analysis, critical revision.

VIII PhD, Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Scientific and intellectual content of the study, analysis and interpretation of data, manuscript writing, critical revision, final approval.


 

Abstract

Purpose: To evaluate PBS®MCIMMO cement in the filling of bone defects.

Methods: Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups.

Results: In all comparisons, significance was observed for group 2 (p = 0.0014–0.0026).

Conclusion: The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.

Key words: Dental Implants. Immediate Dental Implant Loading. Guided Tissue Regeneration,

Periodontal. Bone Substitutes. Rats.


 

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